Animal Welfare

NIEHS | ICCVAM | ECVAM | Animal Alternative - Animal Welfare:

Drik is committed to reduction of animal usage in research studies. We also implement the studies and recommendations of ICCVAM and ECVAM. The Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) was born in September of 1994 as an ad hoc committee of the National Institute of Environmental Health Sciences (NIEHS). Composed of representatives from 15 federal agencies. ICCVAM was created with the purpose of reducing, refining, and replacing the use of animals in toxicological testing.  

The following studies recommended by the agencies are available and check with us on their availability.

  • Acute Toxicity – Measures hazards arising from accidental exposure to a substance, either from ingestion, inhalation, or contact on skin.
  • Ocular Toxicity – Measures ability of a substance to cause temporary or permanent eye damage.
  • Biologics/Vaccines – Measures vaccine potency.
  • Dermal Toxicity – Measures ability of a substance to cause temporary or permanent skin irritation/damage.
  • Immunotoxicity – Measures ability of a substance to cause an allergic reaction, particularly when applied to the skin.
  • Endocrine Disruption – Measures ability of a substance to interfere with the endocrine system (hormones).
  • Pyrogenicity – Measures ability of a substance or device to induce fever.
  • Chronic Toxicity/Carcinogenicity – Measures hazards arising from long-term exposure to a substance, particularly the substance’s ability to damage cellular DNA and/or cause cancer.
  • ICCVAM also identified Neurotoxicty Testing and Reproductive and Developmental Toxicity Testing as areas of interest.

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